Vol 14, No 10 (October 31, 2025): Translational Andrology and Urology

Editorial Commentary

Long-term HIF-2α inhibition in von Hippel-Lindau disease: insights from LITESPARK-004
Yu-Wei Chen, Melis Guer, Rana R. McKay
Translational Andrology and Urology  
2025;
14
(10)
:2781-2785
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 (31 October 2025) 
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Checkmate 274: expanding treatment options for muscle-invasive bladder cancer
Hiten Doshi, Daniel M. Geynisman
Translational Andrology and Urology  
2025;
14
(10)
:2786-2791
.
 (31 October 2025) 
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Original Article

Association between erectile dysfunction and relative fat mass in adult men in the United States
Zhao Luo, Chuan Lin, Jae Heon Kim, Yu Seob Shin, Benjamin I. Chung
Translational Andrology and Urology  
2025;
14
(10)
:2792-2804
.
 (31 October 2025) 
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Combining single-cell and bulk RNA sequencing data to create a reliable prognostic model for predicting clear-cell renal cell carcinoma progression
Yongchen Li, Jingwen Liu, Diman Mai, Renzhi Tan, Chao Wang, Zengnan Mo
Translational Andrology and Urology  
2025;
14
(10)
:2805-2826
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 (31 October 2025) 
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Association between social determinants of health and erectile dysfunction: insights from a nationally representative US sample
Yangyang Mei, Yiming Chen, Wei Xia, Renfang Xu, Dong Xue, Qianfeng Zhuang, Xingliang Feng
Translational Andrology and Urology  
2025;
14
(10)
:2827-2843
.
 (31 October 2025) 
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Predicting bone metastasis and high-grade Gleason scores in prostate cancer: a retrospective study integrating clinical features and magnetic resonance imaging radiomics
Yuling Yang, Bin Zou, Bowen Zheng, Yongfei Guo, Shuiquan Yu, Biwei Chen
Translational Andrology and Urology  
2025;
14
(10)
:2844-2858
.
 (31 October 2025) 
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Histological prostatitis and its influence on benign prostatic hyperplasia: a systematic review and meta-analysis
Yichao Wu, Yaoyao Yao, Bingxin Zhou, Yuewan Fu, XuDong Yu, Lianying Song, Yaosheng Zhang
Translational Andrology and Urology  
2025;
14
(10)
:2859-2872
.
 (31 October 2025) 
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A log odds of positive lymph nodes (LODDS)-based nomogram for survival prediction in elderly bladder cancer patients after radical cystectomy: development and validation using SEER and Chinese cohorts
Tongpeng Liu, Yu Yao, Junlei Huang, Junjie Ji, Lijiang Sun, Guiming Zhang
Translational Andrology and Urology  
2025;
14
(10)
:2873-2884
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 (31 October 2025) 
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Myeloperoxidase inhibits prostate cancer progression, suppresses the PI3K/AKT signaling pathway and reshapes the immune microenvironment
Menghao Zhou, Nanxin Liu, Jianhu Xie, Fanjian Zeng, Shimin Zou, Yunjie Ju, Xing Xiong
Translational Andrology and Urology  
2025;
14
(10)
:2885-2901
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 (31 October 2025) 
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Ursolic acid sensitizes bladder cancer to gemcitabine chemotherapy by concurrently targeting PI3K/AKT and JNK pathways
Xiaolong Huang, Yan Sun, Hang Tong, Junlong Zhu, Juncheng Pan, Peng Wen, Weiyang He
Translational Andrology and Urology  
2025;
14
(10)
:2902-2916
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 (31 October 2025) 
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Clinicopathological features and prognostic factors of clear cell papillary renal cell tumor: a retrospective population-based analysis
Yiguan Qian, Kunlun Zhao, Yang Li, Ning Liu, Chencheng Ji, Paerhati Tuerxun, Xiaotian Jiang, Min Wang, Zhongli Xiong, Ruipeng Jia, Tao Xu, Yu-Zheng Ge
Translational Andrology and Urology  
2025;
14
(10)
:2917-2926
.
 (31 October 2025) 
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Association between delayed graft function and cytomegalovirus infection after renal transplant
Luhao Liu, Rongxin Chen, Jiali Cai, Maierheba Wubuli, Boyu Zheng, Junhan Wang, Xiangyou Li, Yujing Lin, Zheng Chen
Translational Andrology and Urology  
2025;
14
(10)
:2927-2934
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 (31 October 2025) 
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Mean platelet volume is a predictor for abscess formation in patients with epididymitis
Yihong Zhou, Kang Liu, Alex Liu, Peter K. F. Chiu, Jeremy Y. C. Teoh, Chi Fai Ng
Translational Andrology and Urology  
2025;
14
(10)
:2935-2943
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 (31 October 2025) 
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Feasibility analysis of generative artificial intelligence tools as a means of medical science popularization on urological diseases
Wenda Wang, Yi Zhao, Guoyang Zheng, Jianhua Deng
Translational Andrology and Urology  
2025;
14
(10)
:2944-2952
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 (31 October 2025) 
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Single-cell multi-omics and spatial transcriptomics reveal the transcriptional regulatory landscape of clear cell renal cell carcinoma
Juan Duan, Peifeng Ke, Bangqi Wang, Xiaofu Qiu, Yifeng He, Zongtai Zheng, Zemin Wan, Chuling Wu, Zhuoyun Lv
Translational Andrology and Urology  
2025;
14
(10)
:2953-2974
.
 (31 October 2025) 
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Impact of preoperative SARS-CoV-2 infection on post-prostatectomy urinary continence and erectile function
Weitao Zhong, Yilong Gao, Yanxiang Shao, Xiang Li
Translational Andrology and Urology  
2025;
14
(10)
:2975-2984
.
 (31 October 2025) 
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Association of Geriatric Nutritional Risk Index with erectile dysfunction in the elderly population
Biao Zhu, Tuanhong Xia, Li Li, Congling Mao, Le Kang, Zhaofa Yin
Translational Andrology and Urology  
2025;
14
(10)
:2985-2994
.
 (31 October 2025) 
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Preliminary study of ultrasound-guided ilioinguinal-iliohypogastric nerve block in performing low ligation of the spermatic vein
Ronghua Wu, Wengang Hu, Xing Liu, Guiying Yang, Shanhong Yi, Ji Zheng, Maolin Xiao, Weihua Fu
Translational Andrology and Urology  
2025;
14
(10)
:2995-3002
.
 (31 October 2025) 
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Decoding the ceRNA regulatory landscape: a comprehensive transcriptomic analysis of ncRNA-driven bladder fibrosis following spinal cord injury
Jimeng Ruan, Tongwen Ou, Xin Cui, Hao Yan, Bo Cui, Zhenhua Shang
Translational Andrology and Urology  
2025;
14
(10)
:3003-3022
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 (31 October 2025) 
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Body mass index mediates the association between heavy metal exposure and overactive bladder risk: insights from a nationally representative cross-sectional study using explainable machine learning
Benjie Li, Qixian Wang, Jiawei Gui, Zhuoxuan Yu, Xiang Li, Chunfeng Xie, Jingyang Zhao, Xinxin Liu, Yujun Zhang, Jingjing Song, Zhigang Jie, Guoyang Zhang
Translational Andrology and Urology  
2025;
14
(10)
:3023-3041
.
 (31 October 2025) 
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Erectile dysfunction increases the risk of stroke: evidence from NHANES and Mendelian randomization analysis
Bing Zhang, Qingya Yang, Hui Sun, Ming Liu, Hao Liang, Hong Ji
Translational Andrology and Urology  
2025;
14
(10)
:3042-3052
.
 (31 October 2025) 
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Age-related variations in thyroid function hormones indicate the risk of prostate cancer: evidence from a nationally representative dataset
Yanjun Chu, Dapeng Zhang, Yujie Feng
Translational Andrology and Urology  
2025;
14
(10)
:3053-3063
.
 (31 October 2025) 
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Immunotherapy research for prostate cancer from 2000 to 2024: a bibliometric and visualization analysis
Baixin Li, Tao Wu, Minfeng Dong, Kai Ye, Jian Wang, Chengde Ren
Translational Andrology and Urology  
2025;
14
(10)
:3064-3087
.
 (31 October 2025) 
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Clinical features and management strategies of ectopic kidney: a 25-year single-center retrospective analysis
Wencong Han, Jingjing Gao, Shiwei Chen, Zejin Ou, Tai Kang, Xiaoteng Yu, Zheng Zhang, Xuesong Li
Translational Andrology and Urology  
2025;
14
(10)
:3088-3096
.
 (31 October 2025) 
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Integrating transcriptomics, single-cell omics, and deep learning-based histopathological features to identify OLFML3 in bladder cancer
Fazhong Dai, Yifeng He, Xiongsheng Huang, Kangjian Lin, Zongtai Zheng, Xiaofu Qiu
Translational Andrology and Urology  
2025;
14
(10)
:3097-3113
.
 (31 October 2025) 
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Inflammatory index-based nomogram for risk stratification of erectile dysfunction: a cross-sectional study with dual-cohort validation and mendelian randomization analysis
Zhaokun Shi, Yixin Zhang, Shanjin Ma, Chao Zhang, Xiangliang Meng, Jianhui Bai, Wei Hu, Hong Du, Yongcai Yu, Yuli Wu, Donghui Han, Yanan Gu, Weijun Qin, Pang Wang, Li Guo, Keying Zhang
Translational Andrology and Urology  
2025;
14
(10)
:3114-3132
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 (31 October 2025) 
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Proportional, but not absolute, intake of appropriate plant protein is associated with a reduced risk of chronic kidney disease: a cross-sectional study based on NHANES 2005–2018
Zuoxun Xia, Ye Xiong
Translational Andrology and Urology  
2025;
14
(10)
:3133-3143
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 (31 October 2025) 
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Association between early age at menarche and overactive bladder risk in women: insights from NHANES and Mendelian randomization analysis
Guoqiang Huang, Kaiwen Xiao, Shuangquan Lin, Xiongbing Lu
Translational Andrology and Urology  
2025;
14
(10)
:3144-3158
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 (31 October 2025) 
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Icariside II attenuates renal fibrosis through mTOR signaling modulation: an integrated approach combining network pharmacology, molecular dynamics, and in vitro validation
Pan Ding, Jian-Cheng Pan, Wen-Jie Tian, Yong-Jiao Yang, Yu-Hong Feng, Ge Gao, Chang-Li Wu, Zhong-Cheng Xin
Translational Andrology and Urology  
2025;
14
(10)
:3159-3180
.
 (31 October 2025) 
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Targeting FGFR1 enhances olaparib sensitivity via MAPK-mediated BRCA2 downregulation in mCRPC
Jian Chen, Jiarun Lai, Yupeng Chen, Yusen Long, Zhaodong Han, Jiaming Su, Rui Zhou, Ziqing Zhou, Huichan He, Shaoyou Liu, Weide Zhong
Translational Andrology and Urology  
2025;
14
(10)
:3181-3193
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 (31 October 2025) 
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Analysis of risk factors for kidney stones in patients with hyperuricemia: a cross-sectional study based on NHANES
Xiaojing Liu, Jingjing Zhou, Conghui Liu, Feng Shao, Zhongxin Li
Translational Andrology and Urology  
2025;
14
(10)
:3194-3202
.
 (31 October 2025) 
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Association between tacrolimus intrapatient variability and clinical outcomes in kidney transplantation: a retrospective cohort study
Hongsheng Chen, Shuang Liu, Lingling Yu, Yinchu Cheng, Xiaofei Hou, Rongsheng Zhao
Translational Andrology and Urology  
2025;
14
(10)
:3203-3211
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 (31 October 2025) 
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Integrated transcriptomics, proteomics, and metabolomics to uncover inflammatory-metabolic crosstalk and key molecules in a mouse model of hyperoxaluria-induced kidney injury
Bangyu Zou, Meng Shu, Chaoyue Lu, Yiying Jia, Shuwei Zhang, Dongxiang Zhang, Zhaoxin Ying, Ziyu Fang, Yonghan Peng, Xiaofeng Gao
Translational Andrology and Urology  
2025;
14
(10)
:3212-3229
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 (31 October 2025) 
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Efficacy analysis of modified circumcision in the treatment of pediatric concealed penis
Peng Luo, Tingting Xue, Ziran Dai, Xuren Chen, Zexin Guo, Xin Feng, Haiming Cao, Qigen Xie
Translational Andrology and Urology  
2025;
14
(10)
:3230-3245
.
 (31 October 2025) 
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Pre-treatment C-reactive protein level is a prognostic marker of patients treated with immune checkpoint inhibitors for renal cell carcinoma: a systematic review and meta-analysis
Yuta Yamada, Akihiro Matsukawa, Shoji Kimura, Fumihiko Urabe, Ekaterina Laukhtina, Naoki Kimura, Yuji Hakozaki, Hirokazu Kagawa, Takahiro Kimura, Haruki Kume, Shahrokh F. Shariat
Translational Andrology and Urology  
2025;
14
(10)
:3246-3255
.
 (31 October 2025) 
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Associations between metabolic obesity phenotypes and prostate cancer in the U.S. population: a cross-sectional study
Xuefeng Lu, Yanyan Wang, Zhichang Jin, Xiaodong Chen, Cheng Fang
Translational Andrology and Urology  
2025;
14
(10)
:3256-3267
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 (31 October 2025) 
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Sparing urethra in women at the time of cystectomy: retrospective comparison of cystectomies with and without urethrectomy
Andres Matoso, Sonia Kamanda, Sunil Patel, Meghan McNamara, Shirley Wang, Kara A. Lombardo, Jean Hoffman-Censits, Max Kates, Rodrigo Salgado Esteves, Armine Smith
Translational Andrology and Urology  
2025;
14
(10)
:3268-3276
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 (31 October 2025) 
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Identification of molecular subtypes and prognostic risk model of glucocorticoid-related lncRNAs in bladder cancer to evaluate prognosis and immunological characteristics
Liangliang Yu, Song Gao, Dan Li, Xuedong Chen
Translational Andrology and Urology  
2025;
14
(10)
:3277-3297
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 (31 October 2025) 
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Personalized radiotherapy benefit prediction in non-surgically managed prostate adenocarcinoma: a prognostic nomogram for survival risk stratification
Lang Wang, Yong Shi, Can Wei, Junhua Xi, Junfeng Jing, Yanbin Zhang
Translational Andrology and Urology  
2025;
14
(10)
:3298-3308
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 (31 October 2025) 
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Surgical Technique

Excisional urethroplasty and the abdominoperineal approach to posterior urethral stenosis: surgical techniques and considerations for the radiated patient
Bridget L. Findlay, Katherine T. Anderson, Alexandr M. Pinkhasov, Alex J. Miller, Boyd R. Viers
Translational Andrology and Urology  
2025;
14
(10)
:3309-3320
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 (31 October 2025) 
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Large stone in neobladder: percutaneous neocystolithotomy
Haidar Al Saffar, Thirisha Radhakrishnan, Mohammadmehdi Adhami, Jake Tempo, Richard Cetti
Translational Andrology and Urology  
2025;
14
(10)
:3321-3327
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 (31 October 2025) 
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Review Article

Management of pelvic fracture urethral injury
Pankaj Mangalkumar Joshi, Meritxell Costa-Grau, Pawan Kandhari, Saurabh Mahesh Thakkar, Emmanuel Ugbede Oyibo, Jimena Navarro, Sanjay Balwant Kulkarni
Translational Andrology and Urology  
2025;
14
(10)
:3328-3341
.
 (31 October 2025) 
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Robot-assisted reconstruction of posterior urethral stenosis: surgical techniques, graft use, and clinical outcomes
Sasha J. Vereecken, Karen M. Doersch, Brian J. Flynn
Translational Andrology and Urology  
2025;
14
(10)
:3342-3353
.
 (31 October 2025) 
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Management of prostatic necrosis and the devastated bladder outlet—a narrative review
Henriette Veiby Holm, Ole Jacob Nilsen
Translational Andrology and Urology  
2025;
14
(10)
:3354-3366
.
 (31 October 2025) 
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Complications and management of penile enhancement procedures
Michael Pignanelli, J. Matt Williams, Raul E. Fernandez Crespo, Jacob Britt, Justin Parker, Rafael Carrion
Translational Andrology and Urology  
2025;
14
(10)
:3367-3376
.
 (31 October 2025) 
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Contemporary management of radiation-associated posterior urethral stenosis: a narrative review
Samuel J. Ivan, Matthew Lee, Jay Simhan
Translational Andrology and Urology  
2025;
14
(10)
:3377-3386
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 (31 October 2025) 
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Antidiabetic agents and male fertility: unraveling the impact of glucose-lowering therapies on sperm quality in diabetic males—a narrative review
Zuoxi Luo, Li Wang, Jinli Luo, Li Shi, Lina Wang, Guangmei Xie
Translational Andrology and Urology  
2025;
14
(10)
:3387-3401
.
 (31 October 2025) 
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Pharmacotherapy for bladder spasm and irritative lower urinary tract symptoms associated with intravesical therapy for bladder cancer: a review of available evidence
Ahmed Albakr, Vikram M. Narayan, Mark Tyson, Daniel Shoskes, Sandip Vasavada
Translational Andrology and Urology  
2025;
14
(10)
:3402-3412
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 (31 October 2025) 
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Prophylactic adjuvant therapy for postoperative recurrence of urethral stricture: a narrative review
Hongming Chen, Feng Yin, Hao Zhong, Yunqi Mo, Hongtai Tu, Zhubingyun Lai, Ruohui Huang, Junrong Zou, Rihai Xiao
Translational Andrology and Urology  
2025;
14
(10)
:3413-3427
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 (31 October 2025) 
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Case Report

Robot-assisted ureteral reconstruction using buccal mucosal graft for traumatic complete ureteral avulsion: a rare case report
Chatporn Boonyapalanant, Shuzo Hamamoto, Sousuke Niwa, Meita Uchida, Kengo Kawase, Rei Unno, Kenichiro Ishibashi, Kentaro Mizuno, Akio Horiguchi, Takahiro Yasui
Translational Andrology and Urology  
2025;
14
(10)
:3428-3436
.
 (31 October 2025) 
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