Vol 15, No 5 (May 30, 2026): Translational Andrology and Urology

Editorial Commentary

Future direction of systemic therapy for advanced renal cell carcinoma: lessons from final and extended follow-up data from the CheckMate 9ER trial
Hiroki Ishihara
Translational Andrology and Urology  
2026;
15
(5)
:143
.
Prime, trap, and fail: engineering chromatin to potentiate topoisomerase II poisons in prostate cancer
Whi-An Kwon
Translational Andrology and Urology  
2026;
15
(5)
:144
.
Diagnostic potential of urinary PENK methylation for bladder cancer in patients with hematuria: insights from a prospective and multi-institutional study
Dai Koguchi, Izuru Shiba, Yutaka Shiono, Kazumasa Matsumoto
Translational Andrology and Urology  
2026;
15
(5)
:145
.
Patient experience and procedural safety in prostate biopsy: interpreting patient-reported outcome measures in the era of transperineal biopsy
Federica Sordelli, Alessandro Uleri, Guillaume Ploussard, Michael Baboudjian
Translational Andrology and Urology  
2026;
15
(5)
:146
.
When the kidney is at risk: anaesthetic technique as one piece of a larger puzzle
Carlo Andrea Bravi, Alberto Martini
Translational Andrology and Urology  
2026;
15
(5)
:147
.
From trial results to bedside decisions: a time-resolved view of CheckMate-9ER
Hiroshi Fukushima, Soichiro Yoshida, Yasuhisa Fujii
Translational Andrology and Urology  
2026;
15
(5)
:148
.

Original Article

Holmium laser enucleation of the prostate improves the renal insufficiency of benign prostatic hyperplasia with hydronephrosis
Dong-Ya Wang, Jian-Hong Wu, Zhi-Yuan Shen, Zhong-Yun Zhang, Di Wu
Translational Andrology and Urology  
2026;
15
(5)
:149
.
A novel metal-free sling approach for benign prostatic hyperplasia: early results of the Progator procedure with high ejaculatory preservation
Zhao Luo, Dong Won Choi, Sung Chul Kam, Chao Niu, Tae Hyo Kim, Chang Min Lee, Yu Seob Shin, Ki Soo Lee
Translational Andrology and Urology  
2026;
15
(5)
:150
.
In vivo proton magnetic resonance spectroscopy of the human kidney and kidney lesions: new protocol
Tyrone L. R. Humphries, Xin Dong, Sharon J. Del Vecchio, Aaron J. Urquhart, Robert J. Ellis, Hemamali Samaratunga, Julia Watson, Ross S. Francis, Graham J. Galloway, Glenda C. Gobe, Simon T. Wood, Carolyn E. Mountford
Translational Andrology and Urology  
2026;
15
(5)
:151
.
Retrospective cohort study of intracytoplasmic sperm injection outcomes using testicular vs. ejaculated sperm among patients with non-obstructive azoospermia or cryptozoospermia
Claudia G. Durbin, Emily Weidenbaum, Phenix Alcide, Chaya Rothschild, Michael Werner, Jennifer K. Blakemore, Caroline McCaffrey, Bobby B. Najari
Translational Andrology and Urology  
2026;
15
(5)
:152
.
Site-specific heterogeneity in treatment response among patients with metastatic bladder cancer: implications for oligometastatic disease—a retrospective cohort study
Tianwei Wang, Bingjian Wei
Translational Andrology and Urology  
2026;
15
(5)
:153
.
Trends of surgical interventions for nephrolithiasis over the past decade: a population-based analysis
Mandy Hsu, Abdul-Jawad J. Majeed, Jennifer A. Kane, Joseph Y. Clark
Translational Andrology and Urology  
2026;
15
(5)
:154
.
Long-term outcome of male urethral hemangioma: a two-center study
Zi-Yue Ma, Liang Liu, Rong-Hua Wu, Lei Du, Zhen-Yu Cui, Jin-Nian Liu, Jin-Chun Qi
Translational Andrology and Urology  
2026;
15
(5)
:155
.
Association between skeletal muscle index and kidney stones in health screening populations: a single-center cross-sectional study
Lijuan Huang, Jingyu Hu, Xixuan Cai, Hu Li, Xingxiao Pan, Jia Zhang, Tao Chen, Liying Chen
Translational Andrology and Urology  
2026;
15
(5)
:156
.
Differential expression of ALOX15 and GPX4 in the testicular tissue of men with obstructive and non-obstructive azoospermia: a cross-sectional study
Lucija Romac, Pavle Romac, Jelena Schwenner-Radovniković, Marica Maretić, Damir Sapunar
Translational Andrology and Urology  
2026;
15
(5)
:157
.
Comprehensive bioinformatics and experimental analysis of PPOX reveals its carcinogenic effect in clear cell renal cell carcinoma
Kaibin Wang, Lili Wang, Yuanhao Zhang, Dingkun Hou, Lijuan Kang, Zheng Qin, Xiao Zhu, Changying Li, Haitao Wang
Translational Andrology and Urology  
2026;
15
(5)
:158
.
Utilizing intraoperative frozen section examination (IFSE) for diagnosis and treatment in a high-clinical-suspicion prostate cancer (PCa) cohort based on 18F-PSMA PET/CT and MRI: a pilot study
Liang-Yong Zhu, Min Fang, Yang Luan, Tian-Bao Huang, Sheng-Ming Lu, Qin Xiao, Ji Chen, Xiao Tan, Xue-Fei Ding
Translational Andrology and Urology  
2026;
15
(5)
:159
.
Vasectomy in Israel: motivations, satisfaction, regret, and healthcare counseling
Jeny Petlach, Yoram Dekel, Maharan Kabha
Translational Andrology and Urology  
2026;
15
(5)
:160
.
Pulsed Thulium:YAG laser enucleation versus open simple prostatectomy for large-gland benign prostatic hyperplasia: a retrospective comparative observational study
Alberto Zambudio-Munuera, Santiago Chiva-San Román, Irene Millán-Ramos, Miguel Herráez-Marcos, Miguel Arrabal-Martín, Miguel A. Arrabal-Polo
Translational Andrology and Urology  
2026;
15
(5)
:161
.
miR-1251-5p inhibits tumorigenesis and metastasis in renal cell carcinoma by targeting MTHFD2
Yubin Li, Guanghan Fan, Gang Wang, Huadong He
Translational Andrology and Urology  
2026;
15
(5)
:162
.
Bioinformatics analysis and clinical validation identify FBXW9 as a biomarker in bladder urothelial carcinoma
Duanzhuo Li, Weibin Wu, Yuntao Chen, Zhanxi Liang, Qing Zhang, Chao Yuan, Shengjie Liao, Yanli Liao, Wenxia Si, Xin Yu, Mi Huang
Translational Andrology and Urology  
2026;
15
(5)
:163
.
Curcumin improves bladder dysfunction in diabetic rats by attenuating oxidative stress via the Keap1/NRF2/HO-1 pathway
Jun-Hao Zheng, Dao-Feng Zhang, Hao-Rui Li, Rong-Yang Jin, Hao Chen, Hai-Yang Zhang
Translational Andrology and Urology  
2026;
15
(5)
:164
.
Correlation between reproductive hormone levels and genetic abnormalities in patients with non-obstructive azoospermia and oligospermia
Yuhe Fu, Liang Hu, Jinxing Liu, Yuanyuan Pei, Xiaojin Luo, Jiangtao Bai, Weiqiang Liu
Translational Andrology and Urology  
2026;
15
(5)
:165
.
Electrolyte trajectory-based subphenotypes and their association with hospital length of stay in prostate cancer patients
Yujiao Shen, Haojie Xuan, Jie Wang, Yue Hu, Yanling Zhang
Translational Andrology and Urology  
2026;
15
(5)
:166
.
Association between prognostic nutritional index (PNI)/Controlling Nutritional Status (CONUT) score and prognosis in patients with bladder cancer: a systematic review and meta-analysis
Yirun Chen, Junbiao Zheng, Dong Li, Qihang Wu, Qiang Ren
Translational Andrology and Urology  
2026;
15
(5)
:167
.
Long-term pregnancy outcomes after deferential vessel‑sparing microsurgical vasoepididymostomy
Shi-Ying Long, Ming-Kuan Zhou, Kun-Long Lyu, Xin Feng, Yong Gao, Fu-Lin Wang, Wu-Yuan Liao, Ya-Dong Zhang, Xiang-Zhou Sun, Chun-Hua Deng, Xiang-An Tu, Jin-Tao Zhuang
Translational Andrology and Urology  
2026;
15
(5)
:168
.
Advancing urological practice: the value of combined antegrade and retrograde ureterography for the management of complex ureteral strictures
Kangxiang Xu, Manshun Dong, Chaoqi Liang, Ruoyu Li, Qiuxuan Yu, Jin Liu, Hang Yin, Kuibiao Wang, Xincheng Gao, Yuancheng Zhou, Shuaishuai Chai, Xingyuan Xiao, Bing Li
Translational Andrology and Urology  
2026;
15
(5)
:169
.
Recurrence and timing of conversion to radical nephroureterectomy after endoscopic laser ablation for upper tract urothelial carcinoma: a multicenter Japanese study
Shunsuke Tsuzuki, Fumihiko Urabe, Akio Takayanagi, Maki Yoshioka, Daisuke Yamashita, Futoshi Sano, Atsushi Hirabayashi, Masatake Shinohara, Morifumi Hojo, Wataru Fukuokaya, Akihiro Matsukawa, Kagenori Ito, Keiichiro Mori, Takafumi Yanagisawa, Takahiro Kimura; Japanese Thulium Laser Collaborative Group
Translational Andrology and Urology  
2026;
15
(5)
:170
.
Analysis of factors affecting the upstaging and downstaging of renal cell carcinoma from T1 to T3a and the impact of different surgical approaches on patient prognosis and survival: a multicenter retrospective study
Yishuai Zhang, Yelinar Baerbieke, Junjie Fan, Chenhui Ma, Yanxin Zhuang, Jiacheng Li, Zhiyuan Wang, Jin Zeng, Xinyu Shi, Tao Yang, Xinqi Pei, Xudong Li
Translational Andrology and Urology  
2026;
15
(5)
:171
.
Super-selective bladder arterial chemotherapy for muscle invasive bladder cancer
Yawei Li, Yuxi Liu, Junqing Xi, Xiao Li, Xiaowu Zhang
Translational Andrology and Urology  
2026;
15
(5)
:172
.
Development and validation of a machine learning-based radiomics model using 45-keV virtual monoenergetic images for differentiating fat-poor angiomyolipoma from clear cell renal cell carcinoma
Siqing Jing, Jinhua Wang, Xinzhu Zhao, Bin Zeng, Jiali Luo, Zhongxian Yang, Yubao Liu
Translational Andrology and Urology  
2026;
15
(5)
:173
.
Propofol-based versus volatile anesthesia and postoperative immune response in prostate cancer
Yao Wu, Dandan Feng, Xin Xu
Translational Andrology and Urology  
2026;
15
(5)
:174
.
NOX4 suppresses malignant progression in prostate adenocarcinoma and functions as a potential diagnostic biomarker
Jimeng Hu, Min Zhou, Xiaobo Wu, Mengbo Hu
Translational Andrology and Urology  
2026;
15
(5)
:175
.
N-acetylcysteine alleviates experimental autoimmune prostatitis in rats by activating PI3K/Akt/CREB and Keap1/Nrf2 pathways
Changjing Wu, Fudong Fu, Yang Xiong, Feng Qin, Yuhang Liu, Jiuhong Yuan
Translational Andrology and Urology  
2026;
15
(5)
:176
.
The role of lipid-lowering drugs in urologic and male reproductive cancers: a Mendelian randomization study
You-Tu Lin, Jia-Quan Zhou, Cong-Jie Xu, Li-Song Xiao, Lian-Yang Weng, Ying-Guang Li, Yang Wang
Translational Andrology and Urology  
2026;
15
(5)
:177
.
Template-based pelvic lymph node dissection during lateral decubitus-positioned total retroperitoneal laparoscopic radical nephroureterectomy: a step-by-step description of a surgical technique
Jun-Wei Pan, Xiang Zhang, Xue-Jian Zhou, Xian-Jin Wang, Da Xu, Bo-Ke Liu, Xing-Wei Jin, Yi-Han Chen, Bao-Xing Huang, Wei-Chao Tu, Xin-Le Zhang, Dan-Feng Xu, Yuan Shao
Translational Andrology and Urology  
2026;
15
(5)
:178
.
Detection of a group of classic serum tumor markers (CSTMs) aids in the differential diagnosis and disease assessment of upper tract urothelial carcinoma (UTUC)
Jun-Wei Pan, Feng Qi, Xing-Wei Jin, Wei-Chao Tu, Xian-Jin Wang, Xiang Zhang, Yi-Han Chen, Bao-Xing Huang, Fang-Xiu Luo, Dan-Feng Xu, Yuan Shao
Translational Andrology and Urology  
2026;
15
(5)
:179
.

Brief Report

Analysis of real-world re-induction outcomes with nadofaragene firadenovec in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer
Chad Reichard, Andrew Trainer, Katie Grant, Parisa Asgarisabet, Angele Kotomale, Nadia Foskett, Daniel Shoskes
Translational Andrology and Urology  
2026;
15
(5)
:180
.

Study Protocol

An intelligent wearable device based on electrical impedance tomography for dynamic and accurate monitoring of voiding function in patients with benign prostatic hyperplasia: protocol for a single-centre self-controlled diagnostic consistency study
Zhuo Liu, Xiushi Lin, Lin Zhuo, Qiang Li, Jiyuan Chen, Zexin Zhu, Xiaolin Li, Chunlei Xiao, Shudong Zhang, Jiangtao Sun, Ke Liu
Translational Andrology and Urology  
2026;
15
(5)
:181
.

Review Article

Platelet-rich plasma in selected urological conditions: a narrative review of biological rationale, current evidence, and limitations
Long Huang, Zongshuai Gao, Xiang Ren, Zhufan Xu, Changtai Zhu
Translational Andrology and Urology  
2026;
15
(5)
:182
.
PI‑RADS v2.1 for prostate MRI: current applications, ongoing debates, and synergies with advanced technologies—a narrative review
Siying Zhang, Xiaoli Wang, Mingyang Guo, Feng Chen
Translational Andrology and Urology  
2026;
15
(5)
:183
.
Garment fit, scrotal thermoregulation, and male fertility outcomes: a narrative review
Mathew Zleczewski, Nathan Clay, Joshua Lambert, Florian Stroie
Translational Andrology and Urology  
2026;
15
(5)
:184
.
Large language models for post-discharge follow-up in erectile dysfunction care: a narrative review
Yiman Zhang, Bodong Lv, Runnan Xu, Chenghao Shi
Translational Andrology and Urology  
2026;
15
(5)
:185
.
Bacillus Calmette-Guérin therapy in the management of upper tract urothelial carcinoma in-situ: a systematic review
Youssef Garras, Daniah Alsaadi, Ned Kinnear, Derek Hennessey
Translational Andrology and Urology  
2026;
15
(5)
:186
.
Impact of bacteriospermia on sperm DNA fragmentation: a narrative review
Jun Ho Lee, Min Chul Cho
Translational Andrology and Urology  
2026;
15
(5)
:187
.

Letter to the Editor

Rethinking survival visualisation: moving beyond Kaplan-Meier curves and hazard ratios in urology
Shugo Yajima, Soichiro Yoshida, Hitoshi Masuda, Yasuhisa Fujii
Translational Andrology and Urology  
2026;
15
(5)
:188
.
Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: exploratory analysis of the proportional hazards assumption
Shugo Yajima, Soichiro Yoshida, Hitoshi Masuda, Yasuhisa Fujii
Translational Andrology and Urology  
2026;
15
(5)
:189
.