@article{TAU10458,
author = {Thomas Chi and Manint Usawachintachit and Pauline Filippou and David Bayne and Weiguo Hu and Helena Chang and Lei Xia and Qi Chen and Wei Xue and Hui He and Qingzhi Long and Olga Arsovska and Eric Taylor and Ryan Paterson and Roger L. Sur and Ben Chew and Marshall L. Stoller and Jianxing Li},
title = {Significant differences in struvite and cystine stone frequency seen among Chinese nephrolithiasis patients living in North America compared to those living in China},
journal = {Translational Andrology and Urology},
volume = {5},
number = {3},
year = {2016},
keywords = {},
abstract = {Background: Interracial disparities in nephrolithiasis prevalence have been reported, but the interplay between genetics and the environment for urinary stone disease risk factors is poorly understood. To examine how environment may alter genetic predisposition for stone formation, we established the International Chinese Consortium on Nephrolithiasis (ICCON) as a multi-institutional collaboration to examine patterns of nephrolithiasis presentation between Chinese patients living in different countries.
Methods: Chinese patients undergoing percutaneous nephrolithotomy (PCNL) at six participating institutions in China and North America over 4 years were reviewed retrospectively. Patient demographics and clinical data were compared between Chinese patients living in China and North America.
Results: A total of 806 patients were included, encompassing 721 Chinese patients living in China and
85 living in North America. Nephrolithiasis patients living in China were more likely to be male (67% vs. 56%, P=0.02), present at a younger age (48.6±15.0 vs. 55.0±13.0 years, P},
issn = {2223-4691}, url = {https://tau.amegroups.org/article/view/10458}
}