%0 Journal Article
%T Screening for functional kinases in metastatic prostate cancer: a glimmer of hope for kinase inhibition
%A Ornstein, Moshe C.
%A Garcia, Jorge A.
%A Sharifi, Nima
%J Translational Andrology and Urology
%D 2016
%B 2016
%9 
%! Screening for functional kinases in metastatic prostate cancer: a glimmer of hope for kinase inhibition
%K 
%X Understanding the molecular biology of castration-resistant prostate cancer (CRPC) has led to a dramatic paradigm shift in the treatment of patients with metastatic disease where the androgen receptor (AR) is a central therapeutic target in the disease. Despite these major advances, disease biology and the well-recognized heterogeneity of prostate cancer (PCa) are some of the inherent disease-specific issues that continue to affect clinical trial design, drug development and ultimately patient outcomes.
%U https://tau.amegroups.org/article/view/10590
%V 5
%N 4
%P 616-619
%@ 2223-4691