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Practical considerations for DNA fragmentation testing in the management of male fertility

   
@article{TAU14615,
	author = {Jason R. Kovac},
	title = {Practical considerations for DNA fragmentation testing in the management of male fertility},
	journal = {Translational Andrology and Urology},
	volume = {6},
	number = {Suppl 4},
	year = {2017},
	keywords = {},
	abstract = {Over the past decade, the importance of DNA fragmentation has matured as more studies suggested a role in the management of male fertility. As a measure of spermatogenic damage from reactive oxygen species (ROS), DNA fragmentation occurs primarily during posttesticular processing through the epididymis (1,2). Given that spermatozoa are exquisitely sensitive to oxidative stress, varicoceles, a known cause of elevated ROS levels, are theorized to be one of the major contributors.},
	issn = {2223-4691},	url = {https://tau.amegroups.org/article/view/14615}
}