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Differential expression of ALOX15 and GPX4 in the testicular tissue of men with obstructive and non-obstructive azoospermia: a cross-sectional study

   
@article{TAU154398,
	author = {Lucija Romac and Pavle Romac and Jelena Schwenner-Radovniković and Marica Maretić and Damir Sapunar},
	title = {Differential expression of ALOX15 and GPX4 in the testicular tissue of men with obstructive and non-obstructive azoospermia: a cross-sectional study},
	journal = {Translational Andrology and Urology},
	volume = {15},
	number = {5},
	year = {2026},
	keywords = {},
	abstract = {Ferroptosis is an iron-dependent form of non-apoptotic cell death. Oxidative stress (OS), accumulation of ferrous ions, and lipid peroxidation products are key features that induce ferroptosis. This study examined the levels of arachidonate 15-lipoxygenase (ALOX15), which promotes lipid peroxidation, and glutathione peroxidase 4 (GPX4), a vital antioxidant enzyme, in testicular tissue from patients with obstructive azoospermia (OA) and across non-obstructive azoospermia (NOA) subgroups categorized into mild, moderate, and severe hypospermatogenesis (HS).},
	issn = {2223-4691},	url = {https://tau.amegroups.org/article/view/154398}
}