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Adjuvant chemotherapy in bladder cancer patients with histological variants: time to change the approach?

   
@article{TAU25376,
	author = {Luca Afferi and Stefania Zamboni and Philipp Baumeister and Livio Mordasini and Agostino Mattei and Marco Moschini},
	title = {Adjuvant chemotherapy in bladder cancer patients with histological variants: time to change the approach?},
	journal = {Translational Andrology and Urology},
	volume = {8},
	number = {Suppl 3},
	year = {2019},
	keywords = {},
	abstract = {Bladder cancer (BCa) is a common malignancy, with about 81,190 estimated new cases and 17,240 estimated deaths in the United States in 2018 (1). Neoadjuvant cisplatin-based combination chemotherapy (NAC) followed by radical cystectomy (RC) with bilateral pelvic lymph node dissection is currently considered the standard of care in muscle-invasive bladder cancer (MIBC) patients (2).  However, 5 years survival after surgery is approximately 50% (3). In this regard, adjuvant cisplatin based-chemotherapy (AC) improves survival outcomes and should be administered in medically fit, NAC naïve patients with pT3/4 and/or positive nodes diseases at RC (2).},
	issn = {2223-4691},	url = {https://tau.amegroups.org/article/view/25376}
}