AB236. The effect of Xuanju compound capsule combined with bromocriptine on erectile dysfunction due to hyperprolactinemia

Objective: To investigate the effect of Xuanju compound capsule combined with bromocriptine on erectile dysfunction due to hyperprolactinemia.

Methods: Forty-six patients with erectile dysfunction due to hyperprolactinemia were divided into a treatment group (n=23) and a control group (n=23), both treated by bromocriptine and the former given Xuanju compound capsule in addition. After treatment for 12 weeks, comparison were made in erectile function, serum prolactin level and serum testosterone in two groups.

Results: Compared with those before treatment, the erectile function after treatment was significantly improved in two groups (P<0.05), serum prolactin level of all patients after treatment declined significantly to the normal range (P<0.05) and serum testosterone after treatment increased significantly. Then the erectile function after treatment in treatment group was significantly better than that in control group (P<0.05). There was no significant difference in serum prolactin level after treatment between two groups (P>0.05). Serum testosterone after treatment in treatment group was significantly higher than that in control group (P<0.05). The effective rate of erectile function in treatment group was significantly higher than that in control group (P<0.05).

Conclusions: Xuanju compound capsule combined with bromocriptine is highly effective in the treatment of erectile dysfunction due to hyperprolactinemia, and the effect was better than bromocriptine.

Keywords: Hyperprolactinemia; erectile dysfunction; bromocriptine; compound Xuanjun capsule