Is testing of sperm DNA fragmentation (SDF) ready for the basic work-up of male infertility?

The authors have presented an informative manuscript on testing of sperm DNA fragmentation (SDF). They presented background material on the development of these tests, and their discussions were supported by 129 references from PubMed up to June 2016. In the section entitled “Evidence Synthesis”, they reported on 8 SDF tests that have been used clinically. The final section was called “Indications for SDF Testing” and it provided ten practical examples of how these tests were utilized in different cases of male infertility.