Serious complications of collagenase clostridium histiolyticum injection for Peyronie’s disease: more than meets the eye!

The serious adverse effects of collagenase clostridium histiolyticum (CCH) injection for the treatment of Peyronie’s disease include penile hematoma and fracture, yet the broad prevalence of these complications was incompletely understood until recently. Yafi et al. examined the prevalence of these serious complications across members of the Sexual Medicine Society of North America (SMSNA), and their survey results shed important light on practice patterns and complication rates observed by CCH prescribers.