Sperm DNA fragmentation testing: where we stand in 2017

World Health Organization (WHO) defines infertility as the inability of a sexually active, non-contraceptive couple to achieve pregnancy in 1 year (1). Overall, the worldwide incidence is about 15 % and a male factor is responsible in 20–50% of cases (2). Medical history, physical examination and semen analysis remains the corner stone of male infertility workup.