Letter to the Editor
The emerging role of PTBP1 in human cancer: novel prognostic factor in non-muscle invasive bladder cancer
Abstract
Alternative splicing is a sophisticated RNA processing mechanism that expands the coding potential of the genome and the proteomic complexity in higher eukaryotes. Splicing requires the recognition of the intron/exon boundaries by a large ribonucleoprotein complex, named the spliceosome, followed by intron excision and ligation of exons to yield the messenger RNA (mRNA) (1).
