Prostate specific membrane antigen (PSMA) imaging: the past is prologue

In just a few short years prostate-specific membrane antigen (PSMA) positron emission tomography (PET) has transformed the management of prostate cancer patients. Where did this revolutionary idea come from? In this review by Rowe, Gorin and Pomper, several of the pioneers of the “PSMA revolution” provide an overview of the evolution of PSMA PET imaging and its potential future. Here, we cast additional light on the story of PSMA PET.