Hypofractionation in prostate cancer radiotherapy: a step forward towards clinical routine

Radiotherapy (RT) has always been considered one of the most important curative treatment modalities for prostate tumors along with surgery. The debate in prostate cancer treatment has recently focused on hypofractionated RT (HRT), which consists of treatment schedules of shorter- than-standard duration, and delivered with larger fraction- size to reach the same biological equivalent dose (BED) as conventional RT (CRT) on the prostate tumor target.