AB114. Analyses of 77 multilocular cystic renal cell carcinoma cases from a single center

Objective: Multilocular cystic renal cell carcinoma (MCRCC) is a distinct subtype of clear cell renal cell carcinoma. Different from other types of renal cancers, MCRCC has a favorable outcome. The real incidence of MCRCC using the new diagnostic criteria is yet unclear. Large scale study is therefore needed to further identify the characteristics of MCRCC.

Methods: A total of 77 MCRCC cases were identified following the 2004 WHO diagnostic criteria in our institute. Their clinical and radiographical characteristics, surgical management, pathological features, and outcomes were retrospectively reviewed.

Results: The incidence of MCRCC in our renal cell carcinoma (RCC) patients was 1.8% (77/4,189). After a median follow-up period of 51 months, no tumor recurrence or metastasis was found.

Conclusions: The incidence of MCRCC in RCC patients is low. Most cases showed no symptoms, and accurate diagnosis is difficult before surgery. MCRCC carries an excellent prognosis after surgical treatment, regardless of the tumor size. Partial nephrectomy should be considered as the preferable surgical approach for the management of MCRCC. The follow-up interval after surgery can be longer.

Keywords: Renal cancer; pathological features; prognosis