Vol 15, No 4 (April 27, 2026): Translational Andrology and Urology

Editorial Commentary

Prostate cancer screening and evidence: the role of overall survival
Takeshi Takahashi
Translational Andrology and Urology  
2026;
15
(4)
:93
.
Advancing bladder cancer detection: commentary on a urinary DNA methylation diagnostic assay
Igor Duquesne, Mohamad Abou Chakra, Amanda A. Myers, Joost L. Boormans, Dickon Hayne, James A. Brown, Michael A. O’Donnell
Translational Andrology and Urology  
2026;
15
(4)
:94
.
Circulating tumor DNA as a prognostic biomarker in adjuvant nivolumab therapy for high-risk muscle-invasive urothelial carcinoma: insights from CheckMate 274 and beyond
Shugo Yajima, Hitoshi Masuda
Translational Andrology and Urology  
2026;
15
(4)
:95
.
PENK methylation and non-invasive bladder cancer detection
Richard T. Bryan, Anshita Goel, Douglas G. Ward
Translational Andrology and Urology  
2026;
15
(4)
:96
.
Urinary PENK DNA methylation for bladder cancer diagnosis: methodological rigor, interpretive boundaries, and the evidence required for clinical translation
Charlotte Delrue, Matthijs Oyaert, Marijn M. Speeckaert
Translational Andrology and Urology  
2026;
15
(4)
:97
.

Original Article

Construction of a LASSO regression-based predictive model for recurrence of urinary tract stones
Xue-Feng Fu, Qi-Chao Wang, Jun-Zhi Chen, Wei Zhong, Fang-Yuan Wu, Kai Wang, Ping Xie, Zhen-Duo Shi
Translational Andrology and Urology  
2026;
15
(4)
:98
.
Leonurine suppresses renal cell carcinoma progression by targeting the PDK1-mediated Warburg effect
Tiaodi Qian, Xuan Zhou, Jiajie Hu
Translational Andrology and Urology  
2026;
15
(4)
:99
.
Efficacy and safety of tolvaptan in rapidly progressing autosomal dominant polycystic kidney disease: a single-center, prospective, single-arm study
Li Zhou, Wenge Li
Translational Andrology and Urology  
2026;
15
(4)
:100
.
Clinical application of compound tung leaf burn oil dressing in postoperative care following circumcision: evaluation of healing time and patient outcomes
Jiangping Xie, Zhonghong Liao, Zhongxiang Liao, Jinhua Wu, Yanhua Wang, Feng Lin, Peiyan Liu
Translational Andrology and Urology  
2026;
15
(4)
:101
.
Efficacy and safety of a novel 18 mmol/L sodium citrate hemofiltration solution in continuous renal replacement therapy for critically ill patients: a retrospective cohort study
Pei-Hong Zhao, An-Qi Liu, Ya-Lei Chen, Hu-Nan Liu, Zhen Li, Xiao-Lu Zhang, Nian-Fang Lu
Translational Andrology and Urology  
2026;
15
(4)
:102
.
ZJU index and prevalence of kidney stones in US adults: evidence for a threshold association from NHANES 2007–2018
Jiaqing Yang, Jingliang Cao, Jianlin Liu, Qian Cheng, Ai-Ping Nie
Translational Andrology and Urology  
2026;
15
(4)
:103
.
Risk factors for kidney stone recurrence and early prediction models: a systematic review and meta-analysis
Jiayuan Ji, Teng Cui, Kai Dang, Yongan Zhou, Yang Yang, Meiyuan Chen, Xiangyu Wang, Jing Xiao
Translational Andrology and Urology  
2026;
15
(4)
:104
.
Identification and diagnostic model construction of cuproptosis-related biomarkers in bone metastatic prostate cancer
Juan Li, Shaoqin Yao, Junhua Luo, Taiyong Li, Jie Zhang
Translational Andrology and Urology  
2026;
15
(4)
:105
.
Overexpression of SIRT3 ameliorates calcium oxalate crystal-induced renal necroptosis by suppressing the TNF-α/RIPK3/P-MLKL pathway
Shuwei Zhang, Yiying Jia, Meng Shu, Wenxin Lu, Bangyu Zou, Ziyu Fang, Bin Yang, Shaoxiong Ming, Yonghan Peng, Xiaofeng Gao
Translational Andrology and Urology  
2026;
15
(4)
:106
.
DARS2 serves as an independent prognostic factor and participates in multiple biological processes in bladder urothelial carcinoma
Renhui Qiu, Taofa Lin, Li Dong, Miao He, Shilong Deng, Shengfa Xu, Zhen Deng, Cheng Deng, Chunyu Guo
Translational Andrology and Urology  
2026;
15
(4)
:107
.
Spatial multi-omics reveals a cancer-associated fibroblast-T cell niche sustaining tissue-resident immunity in clear-cell renal cell carcinoma
Zhenghui Hu, Feifan Wang, Yiwei Lin
Translational Andrology and Urology  
2026;
15
(4)
:108
.
Transforming postoperative follow-up: telemedicine trends in radical prostatectomy patients
Cassra B. Clark, Jessica Santucci, Mackenzie Goldsmith, Himi Begum, Erik B. Lehman, Jay D. Raman
Translational Andrology and Urology  
2026;
15
(4)
:109
.
Evaluation of human epidermal growth factor receptor 2 (HER2)-related genes revealed that HER2-antibody-drug conjugate (ADC) drugs confer clinical benefits to Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer patients
Wenhao Zhan, Dongxin An, Jiahao Lei, Hiocheng Un, Renxuan Lin, Junxing Chen, Ren Liu, Zongren Wang
Translational Andrology and Urology  
2026;
15
(4)
:110
.
DDR2 expression on circulating lymphocytes and monocytes associates with chronic active antibody-mediated rejection in kidney transplant recipients
Guanghui Li, Luhao Liu, Yuyang Hu, Yuhe Guo, Jiao Wan, Jiali Fang, Jin Su, Zheng Chen
Translational Andrology and Urology  
2026;
15
(4)
:111
.
MDM4 promotes chemoresistance in bladder cancer by attenuating P53-mediated EMT
Saimin Cai, Xuening Ren, Daoqing Xia, Meng Wang, Xin Chen, Yan Zhu, Yan Wang
Translational Andrology and Urology  
2026;
15
(4)
:112
.
Pediatric non-rhabdomyosarcoma bladder tumors (NRBTs): a 20-year retrospective longitudinal cohort study at a tertiary referral center
Yangyue Huang, Yiwei Fang, Hongcheng Song, Weiping Zhang, Ning Sun, Wenwen Han, Guannan Wang, Chao Liu
Translational Andrology and Urology  
2026;
15
(4)
:113
.
The chain mediating role of social support and anxiety between intimacy and self-efficacy in patients with psychogenic erectile dysfunction
Huiyun Liu, Ping Hu, Yan Chen, Wan Wan, Wu Chong, Xue Qin, Shujuan Zheng, Ensi Zhang
Translational Andrology and Urology  
2026;
15
(4)
:114
.
Gasless single-port retroperitoneal laparoscopic adrenalectomy: a novel option for adrenal tumors
Xianda Chen, Zhenhua Liu, Haichao Huang, Mingkun Chen, Lei Bian, Nan Ma, Jun Wang, Hui Han, Kai Yao, Renchun Lai, Yuhui Long, Xia Zheng, Shengjie Guo
Translational Andrology and Urology  
2026;
15
(4)
:115
.
Association between remnant cholesterol inflammation index and erectile dysfunction among U.S. adults: a cross-sectional study
Heyi Chen, Sujun Jia, Liangliang Zheng, Bo Wu, Linjin Li
Translational Andrology and Urology  
2026;
15
(4)
:116
.
Association between systemic inflammatory response index and the prognosis of patients with localized and advanced renal cell carcinoma: a systematic review and meta-analysis
Qiang Dai, Xiaodong Tan, Peng Huang, Jin Zhang, Hongxue Zhu
Translational Andrology and Urology  
2026;
15
(4)
:117
.
Preliminary feasibility and safety of domestic probe-based confocal laser endomicroscopy in the diagnosis of bladder lesions: a prospective single-arm cohort study
Yang Hong, Lizhe An, Luping Yu, Jun Liu, Yiqing Du, Tao Xu
Translational Andrology and Urology  
2026;
15
(4)
:118
.
Oncologic outcomes of transurethral resection versus laser excision for non-muscle invasive bladder cancer: a SEER retrospective cohort study
Yu Xia, Binbin Ma, Tao Huang, Xi Liu
Translational Andrology and Urology  
2026;
15
(4)
:119
.
Machine learning integration of multi-omics data develops a sarcomatoid-related renal cell carcinoma score (SARS) for prognosis stratification and guiding therapy
Dingbang Liu, Xiaozhi Xia, Wei Wang, Tao Jin
Translational Andrology and Urology  
2026;
15
(4)
:120
.
Efficacy analysis of transurethral en bloc resection for bladder tumors ≥3 cm
Tianpeng Zhan, Shujun Yang, Le Kang, Cheng Wang, Biao Zhang, Xinyue Lai, Xuan Li, Shun Guo, Shuang Huang, Xu Zhang, Panfeng Shang, Shengkun Sun
Translational Andrology and Urology  
2026;
15
(4)
:121
.
Bibliometric study on hotspots and trends of immunotherapy for kidney cancer from 2014 to 2024
Qiong Guo, Zhongbiao Nie
Translational Andrology and Urology  
2026;
15
(4)
:122
.
Application of hologram technology combined with 3D printing in transperineal prostate biopsy
Xiao Tan, Qin Xiao, Yong-Quan Gao, Yang Luan, Liang-Yong Zhu, Ji Chen, Xue-Fei Ding
Translational Andrology and Urology  
2026;
15
(4)
:123
.
Bioinformatics analysis and experimental approach identify BRD-family gene DSP as a diagnostic and prognostic indicator in bladder cancer
Zhijiang Liu, Tao Tan, Shiji Li, Yi Wang
Translational Andrology and Urology  
2026;
15
(4)
:124
.
Prostate imaging reporting and data system version 2.1 as a predictor of clinically significant and aggressive prostate cancer: a radical prostatectomy-validated study
Nisanard Pisuchpen, Kulyada Eurboonyanun, Aileen O’Shea, Rita Maria Lahoud, Isha D. Atre, Mukesh Harisinghani
Translational Andrology and Urology  
2026;
15
(4)
:125
.
Distant metastasis prediction in renal carcinoma: a retrospective cohort study using interpretable machine learning
Yaping Wang, Yuanlei Chen, Zhenwei Zhou, Yiming Ding, Jie Yuan
Translational Andrology and Urology  
2026;
15
(4)
:126
.
Development and validation of a discrimination model for benign prostatic hyperplasia: key influencing factors, interaction effects, and the protective role of g-tocopherol
Jian-Gang Mao
Translational Andrology and Urology  
2026;
15
(4)
:127
.
Tea polyphenols suppress the malignant progression of renal cancer cells by targeting Nosip
Jiao Wang, Zheng Huang, Dandan Yang, Junjie Gao, Qing Xu, Menglu Dai, Jun Xia, Jia Ma, Xueshan Pan
Translational Andrology and Urology  
2026;
15
(4)
:128
.
Variant allele frequency as a potential marker in response to frontline systemic therapy for patients with locally advanced and metastatic urothelial carcinoma
Albert Jang, Sulin Wu, Hamsa L. S. Kumar, Ravi K. Kyasaram, Adam C. Calaway, Laura Bukavina, Pedro C. Barata, Prateek Mendiratta, Jorge A. Garcia, Zhengyi Chen, Pingfu Fu, Chen-Han Wilfred Wu, Jason R. Brown
Translational Andrology and Urology  
2026;
15
(4)
:129
.
Comparative performance of five nephrolithometry scoring systems and a novel nomogram for predicting stone-free rate following pediatric percutaneous nephrolithotomy
Shao Zhang, Ruiyu Yue, Xiaochen Wang, Manjiang Sun, Jun Li
Translational Andrology and Urology  
2026;
15
(4)
:130
.
A bioinformatics analysis of the PIEZO channel interaction network and the genes related to glycometabolic reprogramming and mitochondrial oxidative phosphorylation in the progression of prostatic hyperplasia
Yajie Zheng, Fuguang Zhao, Pengwei Xu, Chuchu Zeng, Zongrun Sun, Guanlin Wu, Yibin Wang
Translational Andrology and Urology  
2026;
15
(4)
:131
.
Machine learning-based integration identifies lactylation biomarkers for prognosis prediction and tumor microenvironment modulation in bladder cancer
Xiangcheng Zhou, Lianyang Weng, Taize Sun, Qianshi Jiang, Fanchang Zeng, Congjie Xu, Cheng Chang, Yang Wang, Jiaquan Zhou
Translational Andrology and Urology  
2026;
15
(4)
:132
.
Knowledge mapping of photodynamic therapy in bladder cancer: a bibliometric analysis (2000–2025)
Jilin Yuan, Shaoqiang Xing, Wei Sun, Sheng Zeng, Yaowen Li, Zhaoliang Xu, Yifei Zhang, Xiaoming Liu, Jiazhen Xing, Qian Liu
Translational Andrology and Urology  
2026;
15
(4)
:133
.
Aberrant methylation of mitochondrial genes as a link between oxidative phosphorylation dysregulation and the pathogenesis of hypospadias: a multiomics and clinical sample study
Hongchao Yang, Jian Wang, Youtian Zhang, Wei Wang, Liqiong Guo, Shuhao Shi, Zhenhua Zhang, Yong Guan, Hualei Cui
Translational Andrology and Urology  
2026;
15
(4)
:134
.

Review Article

Research progress on serine proteases in the field of male reproduction: a narrative review
Feng Zhu, Hui Zhu, Tongbing Chen
Translational Andrology and Urology  
2026;
15
(4)
:136
.
Single-port robotic surgery for kidney and upper tract cancer: a narrative review
Karim Daher, Nicolas A. Soputro, Salim K. Younis, Abdulrahman Al-Bayati, Rui Bernardino, Mohamad Watfa, Samarpit Rai, Lin Wang, Rashed Ghandour, Jihad Kaouk, Riccardo Autorino
Translational Andrology and Urology  
2026;
15
(4)
:137
.
Paclitaxel-coated balloon adjunct for benign ureteral and ureteroenteric strictures: a narrative review and translational proposal for enhanced endourological patency
Lucas Diéguez-Álvarez, Jorge Panach-Navarrete, José María Martínez-Jabaloyas
Translational Andrology and Urology  
2026;
15
(4)
:138
.
Does the evidence support circumcision of infant males in the United Kingdom?—a systematic review
Brian J. Morris, Stephen Moreton, Stefan A. Bailis, Mark Sheldon, Jeffrey D. Klausner
Translational Andrology and Urology  
2026;
15
(4)
:139
.

Case Report

“5G wireless + wired network”-based multi-console robotic telesurgery: adaptability to complex surgical procedures and diverse network infrastructures—a case report
Zixing Ye, Yongxue Ding, Weifeng Xu, Yi Xie, Mingwei Qin, Jing Fan, Liang Cui, Na Li, Xin Qiao, Yu Fang, Zhigang Ji, Yan Yang, Jie Dong
Translational Andrology and Urology  
2026;
15
(4)
:140
.
Yolk sac tumor after post-detorsion changes in a torsed undescended testis: a case report
Chenghao Zhanghuang, Qiurong Li, Dewei Zhang, Zhao Yang, Rentao Nong, Fengming Ji, Yucheng Xie, Bing Yan
Translational Andrology and Urology  
2026;
15
(4)
:141
.