miR-1251-5p inhibits tumorigenesis and metastasis in renal cell carcinoma by targeting MTHFD2

Renal cell carcinoma (RCC) is one of the most severe diseases worldwide. More and more studies have found that microRNAs (miRNAs) play very important roles in the occurrence and development of cancer. Previous studies showed that miR-1251-5p is lowly expressed in RCC. However, how miR-1251-5p is involved in regulating the growth and invasion of RCC cells is still unclear. This study aimed to determine the specific effect and molecular mechanism of miR-1251-5p in renal cancer. Our research may provide a new idea for the diagnosis and treatment of RCC.